Magnesium and Nitric Oxide are Best Friends And They’re Your Best Friends Too. Here’s Why


Magnesium is the third most abundant mineral on the planet. That’s probably because it is an essential cell signaling mineral that is critical to all living beings and that includes plants. Nitric oxide is a critical gas in the body that supports respiration, circulation and maintaining homeostasis just to mention a few of its critical functions. There would be no life if the body didn’t produce nitric oxide.

Nitric oxide supplies the body with the ability to build immunity, fight infections, strengthen arterial health while dilating arteries, increasing circulation and lymphatic contraction. Nitric oxide is a gaseous cell signaling molecule produced in the endothelial lining of the artery. It dilates the vessels and allows oxygen to flow freely, transporting much needed oxygen and nutrients to the rest of the body. It lines the nose and mouth and kills bacteria on contact preventing foreign pathogens from entering through these important and exposed orifices.

Nitric oxide is unable to fire without magnesium. These two ingredients are co-dependent. Considering that nitric oxide production decreases every year of life so that by the time one is just 50 he produces about 50% or less of what he produced at 20, it’s easy to understand that bodily functions slow down and problems often begin around this age. When you consider that 80% of Americans are magnesium deficient, getting adequate levels in order to maximize nitric oxide production is necessary. Sufficient magnesium is also essential for the uptake of potassium and thiamine and is required for the conversion of vitamin D into it’s active form in the blood.

What is most notable is that magnesium and nitric oxide work in tandem to accomplish similar tasks. Here is a short list

Both Magnesium and Nitric Oxide deficiency leads to

  • Hypertension (high blood pressure)
  • Diabetes (bcz it’s needed in the metabolic pathways to allow insulin to usher glucose into cells)
  • Cholesterol buildup which is implicated in heart disease

And both help the body to

  • Improve sleep
  • Reduce muscle tension
  • Reduce pain
  • Improve heart function
  • Protect the brain
  • Improve mood
  • Relax blood vessels and allows to dilate
  • Regulate the action of brain neurotransmitters and inflammatory substances
  • Protect the endothelium
  • Inhibit excess platelet aggregation preventing the formation of tiny clots that block blood vessels
  • Prevent inflammation

Probably the most important aspect of the nitric oxide and magnesium co-dependent relationship is in the area of the all-important artery and arterial wall known as the endothelium.

The endothelial cells area a single layer of specialized cells that form the inner part of the membrane of the artery. The subendothelial layer lies just beneath it and it is a thin connective tissue that contains elastin. This is what makes the arteries elastic. Magnesium is essential to maintain healthy elastin. Deficiency in magnesium will degenerate the precious elastin of the artery rendering hardened arteries.

Smooth muscle cells are the next layer which provide integrity and control the dilation of the arterial cavity.

This activity is triggered by the calcium/magnesium ratio in the body. Magnesium causes relaxation and calcium causes contraction and together they control blood pressure and flow in the artery. The final messenger for the dilation response is nitric oxide.

Coronary arteries require even more elasticity than other arteries because they must expand and flex with the expansion and contraction of the heart muscle. Loss of elasticity results in inflammation of the endothelial and subendothelial layers at the junction points that are most mechanically challenged by the expansion and contraction action. Those challenged areas are the areas where arteries bifurcate. This is where clots often lodge and where a break is most likely to occur.

Additionally, when the arterial wall is injured, inflammation is the body’s response to repair. Calcium and magnesium rush to repair the injury and if there is more calcium than magnesium, than calcium precipitates around the area of inflammation causing rigidity and interferes with blood flow.

The brilliant dance between magnesium and nitric oxide work in tandem to maintain the health of the artery and to keep blood flowing and combat inflammation.

Studies show the risk of dying from heart disease in people deficient in magnesium and nitric oxide is higher than those with sufficient levels.

Cardio Miracle contains magnesium threonate which is an important form of magnesium that maintains brain health.Given that 80% of Americans are deficient it would be a good idea to supplement with magnesium chloride while taking Cardio Miracle to ensure you meet your daily requirement of magnesium. In addition, it is advisable to include fresh vegetables rich in magnesium to your daily diet. Seek the advise of your nutritionist or healthcare professional to check your magnesium levels in order to customize a diet that is right for you.

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